The rate of adaptive evolution in enteric bacteria

被引：118

作者：

Charlesworth, Jane ^{[1
]}

Eyre-Walker, Adam

机构：

[1] Univ Sussex, Sch Life Sci, Ctr Study Evolut, Brighton, E Sussex, England

[2] Natl Evolut Synth Ctr, Durham, NH USA

来源：

MOLECULAR BIOLOGY AND EVOLUTION | 2006年 / 23卷 / 07期

基金：

英国生物技术与生命科学研究理事会;

关键词：

adaptive evolution; enteric bacteria; McDonald-Kreitman test;

D O I：

10.1093/molbev/msk025

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Here we estimate the rate of adaptive substitution in a set of 410 genes that are present in 6 Escherichia coli and 6 Salmonella enterica genomes. We estimate that more than 50% of amino acid substitutions in this set of genes have been fixed by positive selection between the E. coli and S: enterica lineages. We also show that the proportion of adaptive substitutions is uncorrelated with the rate of amino acid substitution or gene function but that it may be correlated with levels of synonymous codon usage bias.

引用

页码：1348 / 1356

页数：9

共 61 条

[1]

AKASHI H, 1994, GENETICS, V136, P927

[2] Population history and natural selection shape patterns of genetic variation in 132 genes [J].

Akey, JM ;

Eberle, MA ;

Rieder, MJ ;

Carlson, CS ;

Shriver, MD ;

Nickerson, DA ;

Kruglyak, L .

PLOS BIOLOGY, 2004, 2 (10) :1591-1599

[3] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[4] Contrasting patterns of X-linked and autosomal nucleotide variation in Drosophila melanogaster and Drosophila simulans [J].

Andolfatto, P .

MOLECULAR BIOLOGY AND EVOLUTION, 2001, 18 (03) :279-290

[5] AFRICAN AND NORTH-AMERICAN POPULATIONS OF DROSOPHILA-MELANOGASTER ARE VERY DIFFERENT AT THE DNA LEVEL [J].

BEGUN, DJ ;

AQUADRO, CF .

NATURE, 1993, 365 (6446) :548-550

[6] Linkage limits the power of natural selection in Drosophila [J].

Betancourt, AJ ;

Presgraves, DC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (21) :13616-13620

[7] The genomic rate of adaptive amino acid substitution in Drosophila [J].

Bierne, N ;

Eyre-Walker, A .

MOLECULAR BIOLOGY AND EVOLUTION, 2004, 21 (07) :1350-1360

[8] The complete genome sequence of Escherichia coli K-12 [J].

Blattner, FR ;

Plunkett, G ;

Bloch, CA ;

Perna, NT ;

Burland, V ;

Riley, M ;

ColladoVides, J ;

Glasner, JD ;

Rode, CK ;

Mayhew, GF ;

Gregor, J ;

Davis, NW ;

Kirkpatrick, HA ;

Goeden, MA ;

Rose, DJ ;

Mau, B ;

Shao, Y .

SCIENCE, 1997, 277 (5331) :1453-+

[9] Natural selection on protein-coding genes in the human genome [J].

Bustamante, CD ;

Fledel-Alon, A ;

Williamson, S ;

Nielsen, R ;

Hubisz, MT ;

Glanowski, S ;

Tanenbaum, DM ;

White, TJ ;

Sninsky, JJ ;

Hernandez, RD ;

Civello, D ;

Adams, MD ;

Cargill, M ;

Clark, AG .

NATURE, 2005, 437 (7062) :1153-1157

[10] THE EFFECT OF BACKGROUND SELECTION AGAINST DELETERIOUS MUTATIONS ON WEAKLY SELECTED, LINKED VARIANTS [J].

CHARLESWORTH, B .

GENETICS RESEARCH, 1994, 63 (03) :213-227

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