Generation of CF3-Containing Epoxides and Aziridines by Visible-Light-Driven Trifluoromethylation of Allylic Alcohols and Amines

被引：177

作者：

Kim, Eunjin ^{[1
]}

Choi, Sungkyu ^{[1
]}

Kim, Heejeong ^{[1
]}

Cho, Eun Jin ^{[1
]}

机构：

[1] Hanyang Univ, Dept Chem & Appl Chem, Ansan 426791, Kyeonggido, South Korea

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2013年 / 19卷 / 20期

基金：

新加坡国家研究基金会;

关键词：

epoxides; nucleophilic addition; radical reactions; trifluoromethylation; visible light; PALLADIUM-CATALYZED TRIFLUOROMETHYLATION; OXYTRIFLUOROMETHYLATION; PHOTOCATALYSIS; ALKENES; ACIDS; ARYL;

D O I：

10.1002/chem.201300564

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Radical reactions! Efficient methods for the generation of CF 3-containing epoxides and aziridines have been developed (see scheme). A variety of allylic alcohols and allylic amines were transformed into the corresponding epoxides and aziridines by using [Ru(bpy)3]Cl 2 (bpy=2,2′-bipyridine), CF3I, and 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) (or N,N,N′,N′- tetramethylethylenediamine, TMEDA) under visible-light irradiation. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：6209 / 6212

页数：4

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