Metabolic regulation of potassium channels

被引：51

作者：

Tang, XD ^{[1
]}

Santarelli, LC

Heinemann, SH

Hoshi, T

机构：

[1] Univ Penn, Dept Physiol, Philadelphia, PA 19104 USA

[2] Univ Jena, Fac Med, Res Unit Mol & Cellular Biophys, D-07747 Jena, Germany

来源：

ANNUAL REVIEW OF PHYSIOLOGY | 2004年 / 66卷

关键词：

metabolism; oxygen-sensitive K+ channels; BKCa channels;

D O I：

10.1146/annurev.physiol.66.041002.142720

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Potassium (K+) channels exist in all three domains of organisms: eubacteria, archaebacteria, and eukaryotes. In higher animals, these membrane proteins participate in a multitude of critical physiological processes, including food and fluid intake, locomotion, stress response, and cognitive functions. Metabolic regulatory factors such as O-2, CO2/pH, redox equivalents, glucose/ATP/ADP, hormones, eicosanoids, cell volume, and electrolytes regulate a diverse group of K+ channels to maintain homeostasis.

引用

收藏

页码：131 / 159

页数：29

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