Multidrug-Resistant Tuberculosis (TB) Resistant to Fluoroquinolones and Streptomycin but Susceptible to Second-Line Injection Therapy Has a Better Prognosis than Extensively Drug-Resistant TB

被引：20

作者：

Chan, Edward D. ^{[1
,3
,4
,5
,6
]}

Strand, Matthew J. ^{[9
]}

Iseman, Michael D. ^{[1
,2
,5
,6
,7
,8
]}

机构：

[1] Univ Colorado, Dept Med, Denver, CO USA

[2] Univ Colorado, Natl Jewish Hlth, Dept Med, Denver, CO 80206 USA

[3] Univ Colorado, Cell Biol Program, Natl Jewish Hlth, Denver, CO 80202 USA

[4] Univ Colorado, Denver Vet Adm Med Ctr, Denver, CO 80202 USA

[5] Univ Colorado, Div Pulm Sci, Denver, CO 80202 USA

[6] Univ Colorado, Div Crit Care Med, Denver, CO 80202 USA

[7] Univ Colorado, Div Infect Dis, Denver, CO 80202 USA

[8] Univ Colorado, Hlth Sci Ctr, Denver, CO USA

[9] Univ Colorado, Natl Jewish Hlth, Div Biostat, Denver, CO 80206 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2009年 / 48卷 / 05期

关键词：

TREATMENT OUTCOMES;

D O I：

10.1086/597010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Multidrug-resistant tuberculosis (TB) strains resistant to the fluoroquinolones and streptomycin but susceptible to second-line injection treatment would not be defined as extensively drug-resistant TB. In a cohort of 174 patients with multidrug-resistant TB, we demonstrated that 12 patients with multidrug-resistant TB strains resistant to the fluoroquinolones and streptomycin had significantly better initial and long-term outcomes, compared with 10 patients with extensively drug-resistant TB.

引用

页码：E50 / E52

页数：3

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