Versatile fluorescence labeling method using activated esters on solid support

被引：12

作者：

Chang, YT ^{[1
]}

Schultz, PG ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 17期

关键词：

D O I：

10.1016/S0960-894X(99)00422-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A versatile fluorescence labeling method employing support bound nitrophenyl, N-hydroxysuccinimidyl, 1-hydroxybenzotriazoyl and oxime active esters is described. The relative kinetic properties of different esters were systematically compared using an environment-independent benzoquinoline dye. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2479 / 2482

页数：4

共 16 条

[1] Resin-supported labeling reagents
Adamczyk, M
Fishpaugh, JR
Mattingly, PG
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (02) : 217 - 220
[2] THE UV-VISIBLE ABSORPTION AND FLUORESCENCE OF SOME SUBSTITUTED 1,8-NAPHTHALIMIDES AND NAPHTHALIC ANHYDRIDES
ALEXIOU, MS
TYCHOPOULOS, V
GHORBANIAN, S
TYMAN, JHP
BROWN, RG
BRITTAIN, PI
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1990, (05): : 837 - 842
[3] ACTIVE ESTERS OF POLYMER-BOUND 4-HYDROXY-3-NITROBENZOPHENONE AS USEFUL ACYLATING REAGENTS - APPLICATION TO PEPTIDE-SYNTHESIS
COHEN, BJ
KAROLYHAFELI, H
PATCHORNIK, A
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (05) : 922 - 924
[4] HOBT immobilized on macroporous polystyrene beads: a useful reagent for the synthesis of amides
Dendrinos, K
Jeong, J
Huang, W
Kalivretenos, AG
[J]. CHEMICAL COMMUNICATIONS, 1998, (04) : 499 - 500
[5] Synthesis of N-hydroxysuccinimide esters using polymer bound HOBT.
Dendrinos, KG
Kalivretenos, AG
[J]. TETRAHEDRON LETTERS, 1998, 39 (11) : 1321 - 1324
[6] DUBEY KK, 1995, INDIAN J CHEM B, V34, P876
[7] Solid supported synthesis of hydroxamic acids
Golebiowski, A
Klopfenstein, S
[J]. TETRAHEDRON LETTERS, 1998, 39 (21) : 3397 - 3400
[8] Synthesis of trifluoromethylated dihydro-1,4-oxathin-3-carboxanilides through polymer-bound activated ester
Hahn, HG
Chang, KH
Dal Nam, K
Bae, SY
Mah, H
[J]. HETEROCYCLES, 1998, 48 (11) : 2253 - 2261
[9] Design of novel, potent, noncovalent inhibitors of thrombin with nonbasic P-1 substructures: Rapid structure-activity studies by solid-phase synthesis
Lumma, WC
Witherup, KM
Tucker, TJ
Brady, SF
Sisko, JT
Naylor-Olsen, AM
Lewis, SD
Lucas, BJ
Vacca, JP
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (07) : 1011 - 1013
[10] Encoded combinatorial chemistry: Synthesis and screening of a library of highly functionalized pyrrolidines
Maclean, D
Schullek, JR
Murphy, MM
Ni, ZJ
Gordon, EM
Gallop, MA
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (07) : 2805 - 2810

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