Abnormal products in the Bischler-Napieralski isoquinoline synthesis

被引：36

作者：

Doi, S ^{[1
]}

Shirai, N ^{[1
]}

Sato, Y ^{[1
]}

机构：

[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 15期

关键词：

D O I：

10.1039/a701332i

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of N-[2-(4-methoxyphenyl)ethyl]benzamides with phosphorus pentoxide (and phosphoryl chloride) gives 7-methoxy-1-phenyl-3,4-dihydroisoquinolines (a normal Bischler-Napieralski reaction product) and 6-methoxy-1-phenyl-3,4-dihydroisoquinoli (an abnormal reaction product), The reaction mechanism is discussed.

引用

页码：2217 / 2221

页数：5

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