Hydrogen tunneling in biology

被引:195
作者
Kohen, A
Klinman, JP [1 ]
机构
[1] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
来源
CHEMISTRY & BIOLOGY | 1999年 / 6卷 / 07期
关键词
D O I
10.1016/S1074-5521(99)80058-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The mechanistic details of hydrogen transfer in biological systems ape not fully understood. The traditional approach has been to use semiclassical transition-state theory. This theory cannot explain many experimental findings, however, so different approaches that emphasize the importance of quantum mechanics and dynamic effects should also be considered.
引用
收藏
页码:R191 / R198
页数:8
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