Estimates of ozone depletion and skin cancer incidence to examine the Vienna Convention achievements

被引:191
作者
Slaper, H
Velders, GJM
Daniel, JS
deGruijl, FR
vanderLeun, JC
机构
[1] NATL INST PUBL HLTH & ENVIRONM,AIR RES LAB,NL-3720 BA BILTHOVEN,NETHERLANDS
[2] NOAA,AERON LAB,BOULDER,CO 80303
[3] UNIV UTRECHT,INST DERMATOL,NL-3508 GA UTRECHT,NETHERLANDS
关键词
D O I
10.1038/384256a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
DEPLETION of the ozone layer has been observed on a global scale(1), and is probably related to halocarbon emissions, Ozone depletion increases the biologically harmful solar ultraviolet radiation reaching the surface of the Earth, which leads to a variety of adverse effects, including an increase in the incidence of skin cancer. The 1985 Vienna Convention provided the framework for international restrictions on the production of ozone-depleting substances, The consequences of such restrictions have not yet been assessed in terms of effects avoided. Here we present a new method of estimating future excess skin cancer risks which is used to compare effects of a 'no restrictions' scenario with two restrictive scenarios specified under the Vienna Convention: the Montreal Protocol, and the much stricter Copenhagen Amendments, The no-restrictions and Montreal Protocol scenarios produce a runaway increase in skin cancer incidence, up to a quadrupling and doubling, respectively, by the year 2100. The Copenhagen Amendments scenario leads to an ozone minimum around the year 2000, and a peak relative increase in incidence of skin cancer of almost 10% occurring 60 years later. These results demonstrate the importance of the international measures agreed upon under the Vienna Convention.
引用
收藏
页码:256 / 258
页数:3
相关论文
共 28 条
  • [1] *ALT FLUOR ENV ACC, 1993, PROD SAL ATM REL FLU
  • [2] Early p53 alterations in mouse skin carcinogenesis by UVB radiation: Immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells
    Berg, RJW
    vanKranen, HJ
    Rebel, HG
    deVries, A
    vanVloten, WA
    vanKreijl, CF
    vanderLeun, JC
    deGruijl, FR
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (01) : 274 - 278
  • [3] TOTAL SOLAR-RADIATION AND THE INFLUENCE OF CLOUDS AND AEROSOLS ON THE BIOLOGICALLY EFFECTIVE UV
    BORDEWIJK, JA
    SLAPER, H
    REINEN, HAJM
    SCHLAMANN, E
    [J]. GEOPHYSICAL RESEARCH LETTERS, 1995, 22 (16) : 2151 - 2154
  • [4] ON THE EVALUATION OF HALOCARBON RADIATIVE FORCING AND GLOBAL WARMING POTENTIALS
    DANIEL, JS
    SOLOMON, S
    ALBRITTON, DL
    [J]. JOURNAL OF GEOPHYSICAL RESEARCH-ATMOSPHERES, 1995, 100 (D1) : 1271 - 1285
  • [5] ESTIMATE OF THE WAVELENGTH DEPENDENCY OF ULTRAVIOLET CARCINOGENESIS IN HUMANS AND ITS RELEVANCE TO THE RISK ASSESSMENT OF A STRATOSPHERIC OZONE DEPLETION
    DEGRUIJL, FR
    VANDERLEUN, JC
    [J]. HEALTH PHYSICS, 1994, 67 (04): : 319 - 325
  • [6] DEGRUIJL FR, 1993, CANCER RES, V53, P53
  • [7] UV-INDUCED SKIN-CANCER IN A HAIRLESS MOUSE MODEL
    DEGRUIJL, FR
    FORBES, PD
    [J]. BIOESSAYS, 1995, 17 (07) : 651 - 660
  • [8] DEWINTER R, 1995, 722201005 RIVM
  • [9] SUNLIGHT EXPOSURE, PIGMENTARY FACTORS, AND RISK OF NONMELANOCYTIC SKIN-CANCER .1. BASAL-CELL CARCINOMA
    GALLAGHER, RP
    HILL, GB
    BAJDIK, CD
    FINCHAM, S
    COLDMAN, AJ
    MCLEAN, DI
    THRELFALL, WJ
    [J]. ARCHIVES OF DERMATOLOGY, 1995, 131 (02) : 157 - 163
  • [10] *HLTH COUNC NETH, 1994, UV RAD SUNL