Routine markerless gene replacement in Bacillus anthracis

被引：148

作者：

Janes, BK ^{[1
]}

Stibitz, S ^{[1
]}

机构：

[1] US FDA, Div Bacterial Parasit & Allergen Prod, Ctr Biol Evaluat & Res, Bethesda, MD 20892 USA

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 03期

关键词：

D O I：

10.1128/IAI.74.3.1949-1953.2006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An improved genetic tool suitable for routine markerless allelic exchange in Bacillus anthracis has been constructed. Its utility was demonstrated by the introduction of insertions, deletions, and missense mutations on the chromosome and plasmid pXO1 of the Sterne strain of B. anthracis.

引用

页码：1949 / 1953

页数：5

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