What are the implications of optimism bias in clinical research?

被引：88

作者：

Chalmers, I

Matthews, R

机构：

[1] James Lind Lib, Oxford OX2 7LG, England

[2] Aston Univ, Birmingham B4 7ET, W Midlands, England

来源：

LANCET | 2006年 / 367卷 / 9509期

关键词：

D O I：

10.1016/S0140-6736(06)68153-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：449 / 450

页数：2

共 16 条

[1]

Chalmers I, 2005, CLIN TRIALS, V2, P229

[2] What is the prior probability of a proposed new treatment being superior to established treatments? [J].

Chalmers, I .

BRITISH MEDICAL JOURNAL, 1997, 314 (7073) :74-75

[3] Empirical evidence for selective reporting of outcomes in randomized trials -: Comparison of Protocols to published articles [J].

Chan, AW ;

Hróbjartsson, A ;

Haahr, MT ;

Gotzsche, PC ;

Altman, DG .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (20) :2457-2465

[4] Influence of context effects on health outcomes: a systematic review [J].

Di Blasi, Z ;

Harkness, E ;

Ernst, E ;

Georgiou, A ;

Kleijnen, J .

LANCET, 2001, 357 (9258) :757-762

[5] The uncertainty principle and industry-sponsored research [J].

Djulbegovic, B ;

Lacevic, M ;

Cantor, A ;

Fields, KK ;

Bennett, CL ;

Adams, JR ;

Kuderer, NM ;

Lyman, GH .

LANCET, 2000, 356 (9230) :635-638

[6] REFERENCE BIAS IN REPORTS OF DRUG TRIALS [J].

GOTZSCHE, PC .

BRITISH MEDICAL JOURNAL, 1987, 295 (6599) :654-656

[7]

GOTZSCHE PC, 1990, DAN MED BULL, V37, P329

[8] Contradicted and initially stronger effects in highly cited clinical research [J].

Ioannidis, JPA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 294 (02) :218-228

[9] Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group [J].

Kumar, A ;

Soares, H ;

Wells, R ;

Clarke, M ;

Hozo, L ;

Bleyer, A ;

Reaman, G ;

Chalmers, I ;

Djulbegovic, B .

BMJ-BRITISH MEDICAL JOURNAL, 2005, 331 (7528) :1295-1298B

[10]

KUMAR A, 2005, 13 COCHR C MELB 22 2

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