Inflammatory bowel disease: dogmas and heresies

被引:18
作者
Fiocchi, C [1 ]
机构
[1] Case Western Reserve Univ, Univ Hosp Cleveland, Sch Med, Div Gastroenterol, Cleveland, OH 44106 USA
关键词
Crohn's disease; inflammatory bowel disease; ulcerative colitis;
D O I
10.1016/S1590-8658(02)80153-0
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Perception of a disease state by the practising physician is based on how easily the diagnosis can be made and how predictable the outcome of the chosen therapy is. The academic investigator perceives the same disease based on how well its cause and mechanism are understood, and how rational pathophysiology-based treatments are. Because of incomplete knowledge, neither the practising physician nor the academic investigator are comfortable in dealing with inflammatory bowel disease, and both seek help in the dogmas and heresies inevitably associated with chronic disease of unknown aetiology.
引用
收藏
页码:306 / 311
页数:6
相关论文
共 47 条
[1]  
ALIC M, 1999, AM J GASTROENTEROL, V94, P94
[2]  
Arend P, 1970, Am J Proctol, V21, P331
[3]   THE CURRENT STATUS OF LYMPHOCYTE-T APHERESIS (TLA) TREATMENT OF CROHNS-DISEASE [J].
BICKS, RO ;
GROSHART, KD .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 1989, 11 (02) :136-138
[4]   POSSIBLE ROLE OF MYCOBACTERIA IN INFLAMMATORY BOWEL-DISEASE .1. AN UNCLASSIFIED MYCOBACTERIUM SPECIES ISOLATED FROM PATIENTS WITH CROHNS-DISEASE [J].
CHIODINI, RJ ;
VANKRUININGEN, HJ ;
THAYER, WR ;
MERKAL, RS ;
COUTU, JA .
DIGESTIVE DISEASES AND SCIENCES, 1984, 29 (12) :1073-1079
[5]   Genetics and genetic markers in inflammatory bowel disease [J].
Cho, JH ;
Brant, SR .
CURRENT OPINION IN GASTROENTEROLOGY, 1998, 14 (04) :283-288
[6]   Controversies in pediatric inflammatory bowel disease [J].
Cohen, MB ;
Seidman, E ;
Winter, H ;
Colletti, RB ;
Kirschner, B ;
Balistreri, WF ;
Grand, RJ .
INFLAMMATORY BOWEL DISEASES, 1998, 4 (03) :203-227
[7]   Changing patterns of infectious disease [J].
Cohen, ML .
NATURE, 2000, 406 (6797) :762-767
[8]   Stress and the Gastrointestinal Tract - IV. Modulation of intestinal inflammation by stress: Basic mechanisms and clinical relevance [J].
Collins, SM .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2001, 280 (03) :G315-G318
[9]  
Cottone M, 1999, ITAL J GASTROENTEROL, V31, P503
[10]  
D'Haens GR, 1999, ITAL J GASTROENTEROL, V31, P519