Epidemiological Features of Moyamoya Disease in Japan

被引：68

作者：

Hoshino, Haruhiko ^{[1
,2
]}

Izawa, Yoshikane ^{[3
]}

Suzuki, Norihiro ^{[3
]}

机构：

[1] Tokyo Saiseikai Cent Hosp, Dept Neurol, Minato Ku, Tokyo 1080073, Japan

[2] Tokyo Saiseikai Cent Hosp, Stroke Ctr, Minato Ku, Tokyo 1080073, Japan

[3] Keio Univ, Sch Med, Dept Neurol, Tokyo, Japan

来源：

NEUROLOGIA MEDICO-CHIRURGICA | 2012年 / 52卷 / 05期

关键词：

moyamoya disease; epidemiology; Japanese Ministry of Health; Labour and Welfare; age at onset; clinical feature; CLINICAL-FEATURES;

D O I：

10.2176/nmc.52.295

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To clarify the clinical features of moyamoya disease in Japan, 941 patients with definite moyamoya disease were analyzed from the databases constructed by the Research Committee on Moyamoya Disease, established by the Ministry of Health, Labour and Welfare. Moyamoya disease occurs much more frequently among women than men, with a female-to-male ratio of 1.98. A family history of the disease was observed in 14.9%. The age at onset was characterized by two peaks: one at 5-9 years and another lower peak at around 40 years. Initial clinical features were transient ischemic attack in 46%, infarction in 20%, hemorrhage in 21%, headache in 6%, and epilepsy in 4%. The distribution of the age at onset showed one peak at around 40 years in patients with hemorrhage but two peaks in patients with ischemia.

引用

页码：295 / 298

页数：4

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