Red-Emissive Carbon Dots for Fluorescent, Photoacoustic, and Thermal Theranostics in Living Mice

被引：1184

作者：

Ge, Jiechao ^{[1
]}

Jia, Qingyan ^{[1
,2
]}

Liu, Weimin ^{[1
]}

Guo, Liang ^{[1
]}

Liu, Qingyun ^{[2
]}

Lan, Minhuan ^{[1
]}

Zhang, Hongyan ^{[1
]}

Meng, Xiangmin ^{[1
]}

Wang, Pengfei ^{[1
]}

机构：

[1] Chinese Acad Sci, Tech Inst Phys & Chem, Key Lab Photochem Convers & Optoelect Mat, Beijing 100190, Peoples R China

[2] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266510, Peoples R China

来源：

ADVANCED MATERIALS | 2015年 / 27卷 / 28期

关键词：

carbon dots; fluorescence imaging; photoacoustic imaging; photothermal therapy; theranositcs; GRAPHENE QUANTUM DOTS; GUIDED PHOTOTHERMAL THERAPY; VIVO CANCER-THERAPY; IN-VIVO; PHOTODYNAMIC THERAPY; CONTRAST AGENTS; POLYPYRROLE NANOPARTICLES; MOLECULAR PRECURSORS; MAGNETIC-RESONANCE; IMAGING PROBES;

D O I：

10.1002/adma.201500323

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

Novel red-emissive carbon-dots (C-dots) with broad absorption in the region from 400 to 750 nm are prepared from polythiophene phenylpropionic acid. Upon near infrared laser irradiation, the red-emissive C-dots show strong photoacoustic response and high photothermal conversion efficiency (η ≈ 38.5%). These unique properties enable the C-dots to act as multifunctional fluorescent, photoacoustic, and thermal theranostics for simultaneous diagnosis and therapy of cancer. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4169 / 4177

页数：9

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