Controlling malaria: challenges and solutions

被引：26

作者：

Olliaro, P ^{[1
]}

Taylor, WRJ

Rigal, J

机构：

[1] UNDP, World Bank, WHO Special Program Res & Training Trop Dis, CH-1211 Geneva 27, Switzerland

[2] UCL Royal Free & Univ Coll Med Sch, Ctr Infect Dis, London, England

来源：

TROPICAL MEDICINE & INTERNATIONAL HEALTH | 2001年 / 6卷 / 11期

关键词：

malaria; resistance; sub-Saharan Africa; artemisinin;

D O I：

10.1046/j.1365-3156.2001.00752.x

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Antimalarial drug resistance is a major public health challenge and the principal reason for the erosion of efficacious treatments. Cost and the limited number of antimalarial drugs in current use impose considerable constraints on malaria control, especially in sub-Saharan Africa. The paper describes a multilateral, multidisciplinary research project on artemisinin-based combination therapy, which offers a new and potentially highly effective way to prevent or retard the development of drug resistance.

引用

页码：922 / 927

页数：6

共 28 条

[1]

[Anonymous], 1996, WHOMAL961077

[2]

Bloland PB, 1999, ANN TROP MED PARASIT, V93, P5, DOI 10.1080/00034989958753

[3] BEYOND CHLOROQUINE - IMPLICATIONS OF DRUG-RESISTANCE FOR EVALUATING MALARIA THERAPY EFFICACY AND TREATMENT POLICY IN AFRICA [J].

BLOLAND, PB ;

LACKRITZ, EM ;

KAZEMBE, PN ;

WERE, JBO ;

STEKETEE, R ;

CAMPBELL, CC .

JOURNAL OF INFECTIOUS DISEASES, 1993, 167 (04) :932-937

[4]

BRADLEY DJ, 1997, COMMUN DIS REV, V7, P137

[5] MULTIDRUG RESISTANT FALCIPARUM-MALARIA IN CAMEROON IN 1987-1988 .2. MEFLOQUINE RESISTANCE CONFIRMED INVIVO AND INVITRO AND ITS CORRELATION WITH QUININE RESISTANCE [J].

BRASSEUR, P ;

KOUAMOUO, J ;

MOYOUSOMO, R ;

DRUILHE, P .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1992, 46 (01) :8-14

[6]

DeCock KM, 1997, BRIT MED J, V315, P1

[7] Community based approaches to the control of multidrug resistant tuberculosis: introducing "DOTS-plus" [J].

Farmer, P ;

Kim, JY .

BRITISH MEDICAL JOURNAL, 1998, 317 (7159) :671-674

[8] In vivo efficacy study of amodiaquine and sulfadoxine/pyrimethamine in Kibwezi, Kenya and Kigoma,Tanzania [J].

Gorissen, E ;

Ashruf, G ;

Lamboo, M ;

Bennebroek, J ;

Gikunda, S ;

Mbaruku, G ;

Kager, PA .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2000, 5 (06) :459-463

[9] MORTALITY AND MORBIDITY FROM MALARIA AMONG CHILDREN IN A RURAL AREA OF THE GAMBIA, WEST-AFRICA [J].

GREENWOOD, BM ;

BRADLEY, AK ;

GREENWOOD, AM ;

BYASS, P ;

JAMMEH, K ;

MARSH, K ;

TULLOCH, S ;

OLDFIELD, FSJ ;

HAYES, R .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1987, 81 (03) :478-486

[10] PLASMODIUM-FALCIPARUM-ASSOCIATED ANEMIA IN CHILDREN AT A LARGE URBAN HOSPITAL IN ZAIRE [J].

HEDBERG, K ;

SHAFFER, N ;

DAVACHI, F ;

HIGHTOWER, A ;

LYAMBA, B ;

PALUKU, KM ;

NGUYENDINH, P ;

BREMAN, JG .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1993, 48 (03) :365-371

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