Synthesis and resolution of a C2-symmetrical indolo-2,3-quinodimethane dimer

被引：9

作者：

Diker, K ^{[1
]}

de Maindreville, MD ^{[1
]}

Lévy, J ^{[1
]}

机构：

[1] Univ Reims, Fac Pharm, CNRS, Lab Transformat & Synth Subst Nat, F-51096 Reims, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 42期

关键词：

indoles; dimerisation; resolution; circular dichroism;

D O I：

10.1016/S0040-4039(99)01348-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thermolysis of ethyl 3-dimethylaminomethyl-2-indolylacetate generated an indolo-2,3-quinodimethane as evidenced by its dimerization to a first '4+2' dimer, which rearranged at a higher temperature to a cyclooctadienic diester. Resolution of this last diester in the form of the amides derived from (-)-alpha-methyl-benzylamine proved it to be C-2-symmetrical. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：7459 / 7462

页数：4

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