Structural and signalling molecules come together at tight junctions

被引:259
作者
Tsukita, S [1 ]
Furuse, M [1 ]
Itoh, M [1 ]
机构
[1] Kyoto Univ, Fac Med, Dept Cell Biol, Sakyo Ku, Kyoto 606, Japan
关键词
D O I
10.1016/S0955-0674(99)00016-2
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tight junctions (TJs) have been suggested to act both as barriers and fences, but lack of information on the constituents of TJ strands has hampered the direct assessment of these functions. Over the past year, our understanding of the molecular architecture of TJ strands has increased markedly and we are ready to experimentally examine how TJs are involved in their dual functions.
引用
收藏
页码:628 / 633
页数:6
相关论文
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