Association between obesity measured by different parameters and severity of psoriasis

被引：42

作者：

Duarte, Gleison Vieira ^{[1
]}

Oliveira, Maria de Fatima S. P.

Cardoso, Thiago M. ^{[2
]}

Follador, Ivonise

Silva, Thadeu S.

Cavalheiro, Carolina M. A.

Nonato, Walker ^{[2
]}

Carvalho, Edgar M. ^{[2
,3
]}

机构：

[1] Univ Estado Bahia, Complexo Hosp Univ Prof Edgard Santos, Univ Hosp Prof Edgard Santos, Univ Fed Bahia,Serv Dermatol,Dept Dermatol, BR-40110170 Salvador, BA, Brazil

[2] Univ Estado Bahia, Complexo Hosp Univ Prof Edgard Santos, Univ Hosp Prof Edgard Santos, Dept Immunol,Univ Fed Bahia, Salvador, BA, Brazil

[3] Natl Inst Sci & Technol Trop Dis, CNPq MCT, Nacl Ciencia & Tecnol Doencas Tropicais, Salvador, BA, Brazil

来源：

INTERNATIONAL JOURNAL OF DERMATOLOGY | 2013年 / 52卷 / 02期

关键词：

DISEASE; EPIDEMIOLOGY; PREVALENCE; MODERATE; IMPACT; RISK;

D O I：

10.1111/j.1365-4632.2011.05270.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background Obesity has been associated with the severity of psoriasis, but this relationship is not completely understood. Objectives This study aimed to evaluate associations between the severity of psoriasis and weight excess as determined using a variety of parameters. Methods A cross-sectional study was performed in 296 psoriasis patients. Their body mass index (BMI), waist circumference (WC), and waist : hip ratio (WHR) values were compared with results on a psoriasis area severity index (PASI). Results The frequency of severe psoriasis was higher in men (P < 0.05). Direct correlations were established between PASI scores and each of BMI (R = 0.0154, P = 0.01), WC (R = 0.207, P = 0.001), and WHR (R = 0.164, P = 0.007). Conclusions This study extends previous reports of an association between psoriasis and obesity and shows a direct correlation between obesity as measured according to different parameters and psoriasis severity.

引用

页码：177 / 181

页数：5

共 23 条

[1] Psoriasis and metabolic disease: epidemiology and pathophysiology [J].

Azfar, Rahat S. ;

Gelfand, Joel M. .

CURRENT OPINION IN RHEUMATOLOGY, 2008, 20 (04) :416-422

[2]

Boehncke WH, 2010, BMJ-BRIT MED J, V15, p[340, b5666]

[3] The prevalence of the obesity in patients with moderate to severe psoriasis in Sicily populations [J].

Bongiorno, M. R. ;

Doukaki, S. ;

Rizzo, D. ;

Arico, M. .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (01) :92-93

[4] Psoriasis - epidemiology and clinical spectrum [J].

Christophers, E .

CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2001, 26 (04) :314-320

[5] Chronic inflammation in psoriasis and obesity: Implications for therapy [J].

Hamminga, E. A. ;

van der Lely, A. J. ;

Neumann, H. A. M. ;

Thio, H. B. .

MEDICAL HYPOTHESES, 2006, 67 (04) :768-773

[6] DISEASE CONCOMITANCE IN PSORIASIS [J].

HENSELER, T ;

CHRISTOPHERS, E .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1995, 32 (06) :982-986

[7] Impact of obesity and smoking on psoriasis presentation and management [J].

Herron, MD ;

Hinckley, M ;

Hoffman, MS ;

Papenfuss, J ;

Hansen, CB ;

Callis, KP ;

Krueger, GG .

ARCHIVES OF DERMATOLOGY, 2005, 141 (12) :1527-1534

[8] Relationships between obesity and the clinical severity of psoriasis in Taiwan [J].

Huang, Y-H ;

Yang, L-C ;

Hui, R. C-Y ;

Chang, Y-C ;

Yang, Y-W ;

Yang, C-H ;

Chen, Y-H ;

Chung, W-H ;

Kuan, Y-Z ;

Chiu, C-S .

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2010, 24 (09) :1035-1039

[9]

Instituto Brasileiro de Geografia e Estatistica, 2003, COORD IND PREC PESQ

[10] Obesity in psoriasis: leptin and resistin as mediators of cutaneous inflammation [J].

Johnston, A. ;

Arnadottir, S. ;

Gudjonsson, J. E. ;

Aphale, A. ;

Sigmarsdottir, A. A. ;

Gunnarsson, S. I. ;

Steinsson, J. T. ;

Elder, J. T. ;

Valdimarsson, H. .

BRITISH JOURNAL OF DERMATOLOGY, 2008, 159 (02) :342-350

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