The potential harm of oxygen therapy in medical emergencies

被引:90
作者
Cornet, Alexander D. [1 ,2 ,3 ]
Kooter, Albertus J. [1 ,3 ]
Peters, Mike J. L. [1 ,3 ]
Smulders, Yvo M. [1 ,3 ]
机构
[1] Vrije Univ Amsterdam, Med Ctr, Dept Internal Med, NL-1081 HV Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Med Ctr, Dept Intens Care Med, NL-1081 HV Amsterdam, Netherlands
[3] Vrije Univ Amsterdam, Med Ctr, Inst Cardiovasc Res, NL-1081 HV Amsterdam, Netherlands
关键词
ACUTE MYOCARDIAL-INFARCTION; ACUTE ISCHEMIC-STROKE; CORONARY BLOOD-FLOW; SUPPLEMENTAL OXYGEN; ARTERIAL HYPOXEMIA; ANGINA-PECTORIS; VITAMIN-C; HYPEROXIA; RESUSCITATION; ASSOCIATION;
D O I
10.1186/cc12554
中图分类号
R4 [临床医学];
学科分类号
100218 [急诊医学];
摘要
In medical emergencies, supplemental oxygen is often administrated routinely. Most paramedics and physicians believe that high concentrations of oxygen are life-saving [1]. Over the last century, however, a plethora of studies point to possible detrimental effects of hyperoxia induced by supplemental oxygen in a variety of medical emergencies. This viewpoint provides a historical overview and questions the safety of routine high-dose oxygen administration and is based on pathophysiology and (pre)clinical findings in various medical emergencies.
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页数:6
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