Functions and transcriptional regulation of PAH-inducible human UDP-glucuronosyltransferases

被引：46

作者：

Bock, KW ^{[1
]}

Gschaidmeier, H ^{[1
]}

Heel, H ^{[1
]}

Lehmköster, T ^{[1
]}

Münzel, PA ^{[1
]}

Bock-Hennig, BS ^{[1
]}

机构：

[1] Univ Tubingen, Inst Toxicol, D-72074 Tubingen, Germany

来源：

DRUG METABOLISM REVIEWS | 1999年 / 31卷 / 02期

关键词：

UDP-glucuronyltransferase; human isoforms; induction by dioxins; benzo(a)pyrene metabolism;

D O I：

10.1081/DMR-100101927

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：411 / 422

页数：12

共 45 条

[1] BECKER M, 1990, CURRENT RES PHOTOSYN, V1, P101
[2] QUINOL DIGLUCURONIDES ARE PREDOMINANT CONJUGATED METABOLITES FOUND IN BILE OF RATS FOLLOWING INTRATRACHEAL INSTILLATION OF BENZO[A]PYRENE
BEVAN, DR
SADLER, VM
[J]. CARCINOGENESIS, 1992, 13 (03) : 403 - 407
[3] PARACETAMOL GLUCURONIDATION BY RECOMBINANT RAT AND HUMAN PHENOL UDP-GLUCURONOSYLTRANSFERASES
BOCK, KW
FORSTER, A
GSCHAIDMEIER, H
BRUCK, M
MUNZEL, P
SCHARECK, W
FOURNELGIGLEUX, S
BURCHELL, B
[J]. BIOCHEMICAL PHARMACOLOGY, 1993, 45 (09) : 1809 - 1814
[4] THE INFLUENCE OF ENVIRONMENTAL AND GENETIC-FACTORS ON CYP2D6, CYP1A2 AND UDP-GLUCURONOSYLTRANSFERASES IN MAN USING SPARTEINE, CAFFEINE, AND PARACETAMOL AS PROBES
BOCK, KW
SCHRENK, D
FORSTER, A
GRIESE, EU
MORIKE, K
BROCKMEIER, D
EICHELBAUM, M
[J]. PHARMACOGENETICS, 1994, 4 (04): : 209 - 218
[5] PARACETAMOL AS A TEST DRUG TO DETERMINE GLUCURONIDE FORMATION IN MAN - EFFECTS OF INDUCERS AND OF SMOKING
BOCK, KW
WILTFANG, J
BLUME, R
ULLRICH, D
BIRCHER, J
[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1987, 31 (06) : 677 - 683
[6] Regulation of the human bilirubin UDP-glucuronosyltransferase gene
Brierley, CH
Senafi, SB
Clarke, D
Hsu, MH
Johnson, EF
Burchell, B
[J]. ADVANCES IN ENZYME REGULATION, VOL 36, 1996, 36 : 85 - 97
[7] FUNCTION AND REGULATION OF UDP-GLUCURONOSYLTRANSFERASE GENES IN HEALTH AND LIVER-DISEASE - REPORT OF THE 7TH INTERNATIONAL WORKSHOP ON GLUCURONIDATION, SEPTEMBER-1993, PITLOCHRY, SCOTLAND
BURCHELL, B
COUGHTRIE, MWH
JANSEN, PLM
[J]. HEPATOLOGY, 1994, 20 (06) : 1622 - 1630
[8] Coffman BL, 1997, DRUG METAB DISPOS, V25, P1
[9] CONNEY AH, 1982, CANCER RES, V42, P4875
[10] DUTTON GJ, 1980, GLUCURONIDATION DRUG, P23

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