Skeletal muscle hemodynamics and endothelial function in patients after Fontan operation

被引：55

作者：

Inai, K

Saita, Y

Takeda, S

Nakazawa, M

Kimura, H

机构：

[1] Tokyo Womens Med Univ, Heart Inst Japan, Dept Pediat Cardiol, Shinjuku Ku, Tokyo, Japan

[2] Tokyo Womens Med Univ, Heart Inst Japan, Dept Cardiol, Shinjuku Ku, Tokyo, Japan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 93卷 / 06期

关键词：

D O I：

10.1016/j.amjcard.2003.11.062

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To elucidate the relation between exercise capacity and peripheral hemodynamics in patients after the Fontan operation, near-infrared spectroscopy was performed on the vastus lateralis muscle, and flow-mediated vasodilation of the brachial and posterior tibial arteries was done with high-resolution ultrasonography. In Fontan patients, diminished exercise capacity was related to a reduced blood flow supply and an attenuated post-exercise oxygen resaturation of the working skeletal muscle, which also was related to impaired endothelium-dependent vasodilation. (C) 2004 by Excerpta Medica, Inc.

引用

收藏

页码：792 / 797

页数：6

相关论文

共 20 条

[1] FLOW-MEDIATED AND REFLEX CHANGES IN LARGE PERIPHERAL ARTERY TONE IN HUMANS [J].

ANDERSON, EA ;

MARK, AL .

CIRCULATION, 1989, 79 (01) :93-100

[2] Regional blood flow during exercise in humans measured by near-infrared spectroscopy and indocyanine green [J].

Boushel, R ;

Langberg, H ;

Olesen, J ;

Nowak, M ;

Simonsen, L ;

Bülow, J ;

Kjær, M .

JOURNAL OF APPLIED PHYSIOLOGY, 2000, 89 (05) :1868-1878

[3] NONINVASIVE DETECTION OF ENDOTHELIAL DYSFUNCTION IN CHILDREN AND ADULTS AT RISK OF ATHEROSCLEROSIS [J].

CELERMAJER, DS ;

SORENSEN, KE ;

GOOCH, VM ;

SPIEGELHALTER, DJ ;

MILLER, OI ;

SULLIVAN, ID ;

LLOYD, JK ;

DEANFIELD, JE .

LANCET, 1992, 340 (8828) :1111-1115

[4] Skeletal muscle mass independently predicts peak oxygen consumption and ventilatory response during exercise in noncachectic patients with chronic heart failure [J].

Cicoira, M ;

Zanolla, L ;

Franceschini, L ;

Rossi, A ;

Golia, G ;

Zamboni, M ;

Tosoni, P ;

Zardini, P .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 37 (08) :2080-2085

[5] Exercise limitation in chronic heart failure: Central role of the periphery [J].

Clark, AL ;

PooleWilson, PA ;

Coats, AJS .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 28 (05) :1092-1102

[6] 5-YEAR TO 15-YEAR FOLLOW-UP AFTER FONTAN OPERATION [J].

DRISCOLL, DJ ;

OFFORD, KP ;

FELDT, RH ;

SCHAFF, HV ;

PUGA, FJ ;

DANIELSON, GK .

CIRCULATION, 1992, 85 (02) :469-496

[7] EXERCISE RESPONSES IN PATIENTS WITH CONGENITAL HEART-DISEASE AFTER FONTAN REPAIR - PATTERNS AND DETERMINANTS OF PERFORMANCE [J].

GEWILLIG, MH ;

LUNDSTROM, UR ;

BULL, C ;

WYSE, RKH ;

DEANFIELD, JE .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1990, 15 (06) :1424-1432

[8] Regular physical exercise corrects endothelial dysfunction and improves exercise capacity in patients with chronic heart failure [J].

Hambrecht, R ;

Fiehn, E ;

Weigl, C ;

Gielen, S ;

Hamann, C ;

Kaiser, R ;

Yu, JT ;

Adams, V ;

Niebauer, J ;

Schuler, G .

CIRCULATION, 1998, 98 (24) :2709-2715

[9] Preservation of exercise capacity and lack of peripheral changes in asymptomatic patients with severely impaired left ventricular function [J].

Harrington, D ;

Anker, SD ;

Coats, AJS .

EUROPEAN HEART JOURNAL, 2001, 22 (05) :392-399

[10] Exercise-induced vasodilation in forearm circulation of normal subjects and patients with congestive heart failure: Role of endothelium-derived nitric oxide [J].

Katz, SD ;

Krum, H ;

Khan, T ;

Knecht, M .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1996, 28 (03) :585-590