Pattern electrical stimulation of the human retina

被引:469
作者
Humayun, MS [1 ]
de Juan, E [1 ]
Weiland, JD [1 ]
Dagnelie, G [1 ]
Katona, S [1 ]
Greenberg, R [1 ]
Suzuki, S [1 ]
机构
[1] Johns Hopkins Hosp, Wilmer Ophthalmol Inst, Baltimore, MD 21287 USA
关键词
retinal prosthesis; artificial vision; retinitis pigmentosa; age-related macular degeneration; electrical stimulation;
D O I
10.1016/S0042-6989(99)00052-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Experiments were conducted to study if electrical stimulation of the retinal surface can elicit visual sensation in individuals blind from end-stage retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Under local anesthesia, different stimulating electrodes were inserted through the eyewall and positioned over the surface of the retina. Subjects' psychophysical responses to electrical stimulation were recorded. Subjects perceived simple forms in response to pattern electrical stimulation of the retina. A non-flickering perception was created with stimulating frequencies between 40 and 50 Hz. The stimulation threshold was dependent on the targeted retinal area (macular versus extramacular). (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2569 / 2576
页数:8
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