Approach to the management of allograft recipients following the detection of hepatitis B virus in the prospective organ donor

被引：61

作者：

Chung, RT ^{[1
]}

Feng, S

Delmonico, FL

机构：

[1] Massachusetts Gen Hosp, Dept Med, Gastrointestinal Unit, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Surg, Transplant Unit, Boston, MA 02114 USA

[3] Harvard Univ, Sch Med, Boston, MA 02114 USA

[4] New England Organ Bank Inc, Boston, MA 02114 USA

来源：

AMERICAN JOURNAL OF TRANSPLANTATION | 2001年 / 1卷 / 02期

关键词：

donor; HBV; heart; kidney; liver; transplantation;

D O I：

10.1034/j.1600-6143.2001.10214.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Hepatitis B virus (HBV) is a highly infectious blood-borne pathogen that can be transmitted by a solid organ allograft and result in substantial morbidity and mortality. Recent advances in the management of HBV infection prompt a reappraisal of the approach to the management of allograft recipients from cadaver donors previously exposed to HBV, because of the ongoing shortage of organ donors. This report reviews current knowledge regarding the risk of HBV transmission by an organ from cadaver donors testing positive for markers of HBV infection and makes recommendations for the evaluation, treatment, and surveillance of the allograft recipients.

引用

页码：185 / 191

页数：7

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