Mediterranean diet and cardiovascular health

被引:37
作者
Giugliano, D [1 ]
Esposito, K [1 ]
机构
[1] Second Univ Naples, Cardiovasc Res Ctr, Dept Geriatr & Metab Dis, Div Metab Dis, Naples, Italy
来源
NATURAL PRODUCTS AND MOLECULAR THERAPY | 2005年 / 1056卷
关键词
Mediterranean diet; coronary heart disease; reactive oxygen species; antioxidants; vegetable foods;
D O I
10.1196/annals.1352.012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
Diets that are high in fruits, vegetables, legumes, and whole grains and include fish, nuts, and low-fat dairy products have protective health effects. The traditional Mediterranean diet encompasses these dietary characteristics. Other compounds of the Mediterranean diet, the antioxidants, which exist in abundance in vegetables, fruit, beverages, and also virgin olive oil, may contribute to the prevention of coronary heart disease and possibly several forms of cancer and other diseases, thus providing a plausible explanation for its apparent benefits. It may be misleading to focus on a single element of the diet; this may explain, at least in part, the disappointing and frustrating results obtained in trials with vitamin supplementation, prematurely thought to be "the magic bullet" for preventing a myriad of chronic diseases. The results of intervention studies aimed at evaluating whether Mediterranean-type diets are superior to classic diets in the secondary prevention of coronary heart disease have all been encouraging. The biologic mechanisms by which these compounds might exert their effects include, among others, antioxidant functions and induction of detoxification enzymes. However, from a public health perspective it is not essential to wait for elucidation of every mechanism underlying health promotion activities and interventions; given the simplicity of the diet quality score, increasing the intake of recommended foods represents a practical recommendation for improving health.
引用
收藏
页码:253 / 260
页数:8
相关论文
共 19 条
[1]
Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction - Final report of the Lyon Diet Heart Study [J].
de Lorgeril, M ;
Salen, P ;
Martin, JL ;
Monjaud, I ;
Delaye, J ;
Mamelle, N .
CIRCULATION, 1999, 99 (06) :779-785
[2]
Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome - A randomized trial [J].
Esposito, K ;
Marfella, R ;
Ciotola, M ;
Di Palo, C ;
Giugliano, F ;
Giugliano, G ;
D'Armiento, M ;
D'Andrea, F ;
Giugliano, D .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (12) :1440-1446
[3]
Giugliano D, 2001, CIRCULATION, V104, pE34
[4]
GIUGLIANO D, 2000, MEDITERRANEAN DIET O
[5]
GIUGLIANO D, 2001, WAY THEY ATE ORIGINS
[6]
Halliwell B, 1996, ANNU REV NUTR, V16, P33, DOI 10.1146/annurev.nu.16.070196.000341
[7]
Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women - The HALE project [J].
Knoops, KTB ;
de Groot, LCPGM ;
Kromhout, D ;
Perrin, AE ;
Moreiras-Varela, O ;
Menotti, A ;
van Staveren, WA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (12) :1433-1439
[8]
Antioxidant vitamin supplements and cardiovascular disease [J].
Kris-Etherton, PM ;
Lichtenstein, AH ;
Howard, BV ;
Steinberg, D ;
Witztum, JL .
CIRCULATION, 2004, 110 (05) :637-641
[9]
Coronary heart disease incidence in northern and southern European populations: a reanalysis of the seven countries study for a European coronary risk chart [J].
Menotti, A ;
Lanti, H ;
Puddu, PE ;
Kromhout, D .
HEART, 2000, 84 (03) :238-244
[10]
Meta-analysis: High-dosage vitamin E supplementation may increase all-cause mortality [J].
Miller, ER ;
Pastor-Barriuso, R ;
Dalal, D ;
Riemersma, RA ;
Appel, LJ ;
Guallar, E .
ANNALS OF INTERNAL MEDICINE, 2005, 142 (01) :37-46