A preliminary quantitative analysis of REM sleep chin EMG in Parkinson's disease with or without REM sleep behavior disorder

被引：40

作者：

Ferri, Raffaele ^{[1
]}

Fulda, Stephany ^{[1
]}

Cosentino, Filomena I. I. ^{[1
]}

Pizza, Fabio ^{[2
]}

Plazzi, Giuseppe ^{[2
]}

机构：

[1] Oasi Inst IRCCS, Sleep Res Ctr, Dept Neurol IC, Troina, Italy

[2] Univ Bologna, Dept Neurol Sci, Bologna, Italy

来源：

SLEEP MEDICINE | 2012年 / 13卷 / 06期

关键词：

REM sleep behavior disorder; Parkinson's disease; REM sleep Atonia Index; Chin EMG analysis; REM sleep without atonia; Synucleinopathies; RESTLESS-LEGS-SYNDROME; LUMBAR MOTONEURONS; MUSCLE; PRAMIPEXOLE; DIAGNOSIS; FEATURES; ASSOCIATION; AMPLITUDE; ATONIA; STATE;

D O I：

10.1016/j.sleep.2012.01.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objectives: To compare REM sleep chin EMG quantitative features between Parkinson's disease (PD) patients with or without REM sleep behavior disorder (RBD). Subjects and methods: Twenty-seven consecutive PD patients (mean age 67.9 years) and 19 normal controls (mean age 67.5 years) were enrolled. Detailed clinical, laboratory, and polysomnographic studies were obtained in all participants and characteristics of chin electromyographic amplitude during rapid eye movements sleep were analyzed by means of an automatic quantitative approach (Atonia Index). Results: Sixteen of the 27 patients were affected by RBD. An Atonia Index below 0.90 showed high sensitivity (0.938) and specificity (0.909) for the diagnosis of RBD within the group of PD patients. Conclusion: This study recommends the Atonia Index as an objective measure to support and aid the diagnosis of RBD in PD. (C) 2012 Elsevier B.V. All rights reserved.

引用

页码：707 / 713

页数：7

共 48 条

[1] Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology - A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health [J].

Allen, RP ;

Picchietti, D ;

Hening, WA ;

Trenkwalder, C ;

Walters, AS ;

Montplaisi, J .

SLEEP MEDICINE, 2003, 4 (02) :101-119

[2]

[Anonymous], 2005, Diagnostic and coding manual, P148

[3]

Benninger D, 2008, NEUROLOGY, V71, P955, DOI 10.1212/01.wnl.0000327854.15357.eb

[4] REM sleep behavior disorder Updated review of the core features, the REM sleep behavior disorder-neurodegenerative disease association, evolving concepts, controversies, and future directions [J].

Boeve, Bradley F. .

YEAR IN NEUROLOGY 2, 2010, 1184 :15-54

[5] Unraveling the Mechanisms of REM Sleep Atonia [J].

Brooks, Patricia L. ;

Peever, John H. .

SLEEP, 2008, 31 (11) :1492-1497

[6]

Burns Joseph W, 2007, Sleep, V30, P1771

[7] Endogenous excitatory drive modulating respiratory muscle activity across sleep-wake states [J].

Chan, Erin ;

Steenland, Hendrik W. ;

Liu, Hattie ;

Horner, Richard L. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 174 (11) :1264-1273

[8]

CHASE MH, 1989, J NEUROSCI, V9, P743

[9]

Cohen J., 1988, Statistical power analysis for the behavioral sciences, VSecond

[10] Restoration of normal motor control in Parkinson's disease during REM sleep [J].

De Cock, Valerie Cochen ;

Vidailhet, Marie ;

Leu, Smaranda ;

Texeira, Antonio ;

Apartis, Emmanuelle ;

Elbaz, Alexis ;

Roze, Emmanuel ;

Willer, Jean Claude ;

Derenne, Jean Philippe ;

Agid, Yves ;

Arnulf, Isabelle .

BRAIN, 2007, 130 :450-456

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