The potential of muscle stem cells

被引：189

作者：

Seale, P

Asakura, A

Rudnicki, MA

机构：

[1] McMaster Univ, Dept Biol, Hamilton, ON L8S 4K1, Canada

[2] Ottawa Hlth Res Inst, Program Mol Med, Ottawa, ON K1H 8L6, Canada

来源：

DEVELOPMENTAL CELL | 2001年 / 1卷 / 03期

基金：

美国国家卫生研究院; 加拿大健康研究院;

关键词：

D O I：

10.1016/S1534-5807(01)00049-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Skeletal muscle contains two types of stem cells: satellite cells, which function as myogenic precursors, and a population of multipotent adult stem cells. Satellite cells are believed to form a stable, self-renewing pool of stem cells in adult muscle where they function in tissue growth and repair. An additional stem cell population in adult muscle displays a remarkable capacity to differentiate into hematopoietic cells as well as muscle following transplantation. This article discusses the characteristics and properties of these cell populations, the relationship between them, and the potential for stem cell-based muscle therapeutics. © 2001 Cell Press.

引用

收藏

页码：333 / 342

页数：10

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