Novel tryptophan-derived dipeptides and bioactive metabolites from the sea hare Aplysia dactylomela

被引：32

作者：

Appleton, DR

Babcock, RC

Copp, BR

机构：

[1] Univ Auckland, Dept Chem, Auckland, New Zealand

[2] Univ Auckland, Leigh Marine Lab, Auckland, New Zealand

来源：

TETRAHEDRON | 2001年 / 57卷 / 51期

关键词：

sea hare metabolites; dactylamide; biologically active compounds; sea hare ink; laurene derivatives;

D O I：

10.1016/S0040-4020(01)01044-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Dactylamides A (1) and B (2), two new tryptophan-derived dipeptides were isolated from the sea hare Aplysia dactylomela and structurally characterised by spectroscopic methods and synthesis of deoxy-analogues. Isolaurenisol, allolaurinterol, their respective acetates and aplysioviolin, isolated as the bioactive constituents of the sea hare, were also structurally characterised and evaluated in a range of biological assays. (C) 2001 Elsevier Science Ltd. All rights reserved.

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收藏

页码：10181 / 10189

页数：9

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