Urea-hydrogen peroxide (UHP) oxidation of thiols to the corresponding disulfides promoted by maleic anhydride as mediator

被引：50

作者：

Karami, B ^{[1
]}

Montazerozohori, M

Habibi, MH

机构：

[1] Univ Yasuj, Dept Chem, Yasuj 75914353, Iran

[2] Isfahan Univ, Dept Chem, Esfahan 81745117, Iran

来源：

MOLECULES | 2005年 / 10卷 / 10期

关键词：

UHP; thiols; disulfides; oxidation;

D O I：

10.3390/10101385

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Urea-hydrogen peroxide (UHP) was used in the presence of maleic anhydride as mediator in a simple and convenient method for the oxidation in high yield of some thiols to the corresponding disulfides. Peroxymaleic acid formed in situ from the reaction of UHP with maleic anhydride has a key role in this oxidation. Performance of the reaction in various solvents showed that methanol was the solvent of choice at 0 degrees C. The products were isolated by simple filtration on silica gel.

引用

页码：1358 / 1363

页数：6

共 37 条

[1]

CATALYTIC-OXIDATION OF MERCAPTANS BY IODINE HYDROGEN IODIDE SYSTEM IN DIMETHYL-SULFOXIDE [J].