A COMPARISON OF NEURAL MECHANISMS IN MIRROR THERAPY AND MOVEMENT OBSERVATION THERAPY

被引：45

作者：

Wang, Jing ^{[1
,2
,3
]}

Fritzsch, Claire ^{[1
,4
]}

Bernarding, Johannes ^{[4
]}

Holtze, Susanne ^{[4
]}

Mauritz, Karl-Heinz ^{[1
,3
]}

Brunetti, Maddalena ^{[1
,4
]}

Dohle, Christian ^{[1
,4
,5
]}

机构：

[1] MEDIAN Klin Berlin Kladow, D-14089 Berlin, Germany

[2] Jiaxing Univ, Affiliated Hosp 2, Ctr Rehabil, Jiaxing, Peoples R China

[3] Charite, Dept Neurol, Berlin, Germany

[4] Charite, Ctr Stroke Res Berlin, D-13353 Berlin, Germany

[5] Univ Potsdam, Ctr Rehabil Sci, Potsdam, Germany

来源：

JOURNAL OF REHABILITATION MEDICINE | 2013年 / 45卷 / 04期

基金：

美国国家科学基金会;

关键词：

fMRI; mirror; movement; observation; precuneus; RANDOMIZED CONTROLLED-TRIAL; STROKE; REHABILITATION; FMRI;

D O I：

10.2340/16501977-1127

中图分类号：

R49 [康复医学];

学科分类号：

100232 [康复医学];

摘要：

Objective: To compare lateralized cerebral activations elicited during self-initiated movement mirroring and observation of movements. Subjects: A total of 15 right-handed healthy subjects, age range 22-56 years. Methods: Functional imaging study comparing movement mirroring with movement observation, in both hands, in an otherwise identical setting. Imaging data were analysed using statistical parametric mapping software, with significance threshold set at p<0.01 (false discovery rate) and a minimum cluster size of 20 voxels. Results: Movement mirroring induced additional activation in primary and higher-order visual areas strictly contralateral to the limb seen by the subject. There was no significant difference of brain activity when comparing movement observation of somebody else's right hand with left hand. Conclusion: Lateralized cerebral activations are elicited by inversion of visual feedback (movement mirroring), but not by movement observation.

引用

页码：410 / 413

页数：4

共 22 条

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