Recovery of a Functional Class 2 Integron from an Escherichia coli Strain Mediating a Urinary Tract Infection

被引:44
作者
Marquez, Carolina [1 ]
Labbate, Maurizio [3 ]
Ingold, Ana J. [1 ]
Chowdhury, Piklu Roy [3 ]
Ramirez, Maria S. [4 ]
Centron, Daniela [4 ]
Borthagaray, Graciela [2 ]
Stokes, H. W. [3 ]
机构
[1] UDELAR, Catedra Microbiol, Inst Quim Biol, Fac Ciencias, Montevideo, Uruguay
[2] UDELAR, Catedra Microbiol, Fac Quim, Montevideo, Uruguay
[3] Macquarie Univ, Dept Chem & Biomol Sci, Sydney, NSW 2109, Australia
[4] Univ Buenos Aires, Fac Med, Dept Microbiol Parasitol & Immunol, Buenos Aires, DF, Argentina
基金
英国医学研究理事会;
关键词
D O I
10.1128/AAC.00710-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A class 2 integron was found in an Escherichia coli isolate mediating a urinary tract infection. Unlike other class 2 integrons from pathogens, the encoded IntI2 protein was functional. The integron possessed a dfrA14 cassette, and a second novel cassette in which a lipoprotein signal peptidase gene is predicted.
引用
收藏
页码:4153 / 4154
页数:2
相关论文
共 24 条
[1]   A NOVEL INTEGRON-LIKE ELEMENT CARRYING THE METALLO-BETA-LACTAMASE GENE BLA(IMP) [J].
ARAKAWA, Y ;
MURAKAMI, M ;
SUZUKI, K ;
ITO, H ;
WACHAROTAYANKUN, R ;
OHSUKA, S ;
KATO, N ;
OHTA, M .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (07) :1612-1615
[2]   A comparison of antibiotic resistance integrons in cattle from separate beef meat production systems at slaughter [J].
Barlow, R. S. ;
Fegan, N. ;
Gobius, K. S. .
JOURNAL OF APPLIED MICROBIOLOGY, 2008, 104 (03) :651-658
[3]   Diverse class 2 integrons in bacteria from beef cattle sources [J].
Barlow, Robert S. ;
Gobius, Kari S. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 58 (06) :1133-1138
[4]   Isolation and characterization of integron-containing bacteria without antibiotic selection [J].
Barlow, RS ;
Pemberton, JM ;
Desmarchelier, PM ;
Gobius, KS .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (03) :838-842
[5]   Integrons: mobilizable platforms that promote genetic diversity in bacteria [J].
Boucher, Yan ;
Labbate, Maurizio ;
Koenig, Jeremy E. ;
Stokes, H. W. .
TRENDS IN MICROBIOLOGY, 2007, 15 (07) :301-309
[6]   Identification of plasmids by PCR-based replicon typing [J].
Carattoli, A ;
Bertini, A ;
Villa, L ;
Falbo, V ;
Hopkins, KL ;
Threlfall, EJ .
JOURNAL OF MICROBIOLOGICAL METHODS, 2005, 63 (03) :219-228
[7]   Binding of the purified integron DNA integrase Intl1 to integron- and cassette-associated recombination sites [J].
Collis, CM ;
Kim, MJ ;
Stokes, HW ;
Hall, RM .
MOLECULAR MICROBIOLOGY, 1998, 29 (02) :477-490
[8]   Integron-encoded Intl integrases preferentially recognize the adjacent cognate attl site in recombination with a 59-be site [J].
Collis, CM ;
Kim, MJ ;
Stokes, HW ;
Hall, RM .
MOLECULAR MICROBIOLOGY, 2002, 46 (05) :1415-1427
[9]   Efficiency of recombination reactions catalyzed by class 1 integron integrase IntI1 [J].
Collis, CM ;
Recchia, GD ;
Kim, MJ ;
Stokes, HW ;
Hall, RM .
JOURNAL OF BACTERIOLOGY, 2001, 183 (08) :2535-2542
[10]   Antimicrobial resistance and spread of class 1 integrons among Salmonella serotypes [J].
Guerra, B ;
Soto, S ;
Cal, S ;
Mendoza, MC .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (08) :2166-2169