Topology of Blood Transport in the Human Left Ventricle by Novel Processing of Doppler Echocardiography

被引：67

作者：

Hendabadi, Sahar ^{[1
]}

Bermejo, Javier ^{[2
,3
]}

Benito, Yolanda ^{[2
,3
]}

Yotti, Raquel ^{[2
,3
]}

Fernandez-Aviles, Francisco ^{[2
,3
]}

del Alamo, Juan C. ^{[4
]}

Shadden, Shawn C. ^{[1
,5
]}

机构：

[1] IIT, Dept Mech Mat & Aerosp Engn, Chicago, IL USA

[2] Univ Gregorio Maranon, Gen Hosp, Dept Cardiol, Madrid, Spain

[3] Inst Invest Sanitaria Gregorio Maranon, Madrid, Spain

[4] Univ Calif San Diego, Inst Engn Med, Dept Mech & Aerosp Engn, La Jolla, CA 92093 USA

[5] Univ Calif Berkeley, Dept Mech Engn, Berkeley, CA 94720 USA

来源：

ANNALS OF BIOMEDICAL ENGINEERING | 2013年 / 41卷 / 12期

关键词：

Cardiomyopathy; Intracardiac blood flow; Lagrangian coherent structures; Velocimetry; LAGRANGIAN COHERENT STRUCTURES; PARTICLE IMAGE VELOCIMETRY; MAGNETIC-RESONANCE; DIASTOLIC FUNCTION; HEART-FAILURE; IN-VIVO; FLOW; PATTERNS; VALVE;

D O I：

10.1007/s10439-013-0853-z

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Novel processing of Doppler-echocardiography data was used to study blood transport in the left ventricle (LV) of six patients with dilated cardiomyopathy and six healthy volunteers. Bi-directional velocity field maps in the apical long axis of the LV were reconstructed from color-Doppler echocardiography. Resulting velocity field data were used to perform trajectory-based computation of Lagrangian coherent structures (LCS). LCS were shown to reveal the boundaries of blood injected and ejected from the heart over multiple beats. This enabled qualitative and quantitative assessments of blood transport patterns and residence times in the LV. Quantitative assessments of stasis in the LV are reported, as well as characterization of LV vortex formations from E-wave and A-wave filling.

引用

收藏

页码：2603 / 2616

页数：14

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