Resistin: an adipocyte-derived hormone. Has it a role in diabetes and obesity?

被引:82
作者
Rea, R [1 ]
Donnelly, R [1 ]
机构
[1] Univ Nottingham, Sch Med & Surg Sci, Ctr Integrated Syst Biol & Med, Nottingham NG7 2RD, England
关键词
adipocyte-derived hormone; obesity; resistin; thiazolidinedione; type; 2; diabetes;
D O I
10.1111/j.1462-8902.2004.00334.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:163 / 170
页数:8
相关论文
共 58 条
[1]   The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor [J].
Ahmed, Z ;
Smith, BJ ;
Pillay, TS .
FEBS LETTERS, 2000, 475 (01) :31-34
[2]   Dimerization of resistin and resistin-like molecules is determined by a single cysteine [J].
Banerjee, RR ;
Lazar, MA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (28) :25970-25973
[3]  
Beltowski Jerzy, 2003, Med Sci Monit, V9, pRA55
[4]   Resistin and RELM-α gene expression in white adipose tissue of lactating mice [J].
Bing, C ;
Gomez-Ambrosi, J ;
Zabalegui, N ;
Williams, G ;
Trayhurn, P .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 296 (02) :458-462
[5]   Inhibition of adipocyte differentiation by resistin-like molecule α -: Biochemical characterization of its oligomeric nature [J].
Blagoev, B ;
Kratchmarova, I ;
Nielsen, MM ;
Fernandez, MM ;
Voldby, J ;
Andersen, JS ;
Kristiansen, K ;
Pandey, A ;
Mann, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (44) :42011-42016
[6]   Differential dimerization and association among resistin family proteins with implications for functional specificity [J].
Chen, J ;
Wang, L ;
Boeg, YS ;
Xia, B ;
Wang, J .
JOURNAL OF ENDOCRINOLOGY, 2002, 175 (02) :499-504
[7]   Growth hormone rapidly induces resistin gene expression in white adipose tissue of spontaneous dwarf (SDR) rats [J].
Delhanty, PJD ;
Mesotten, D ;
McDougall, F ;
Baxter, RC .
ENDOCRINOLOGY, 2002, 143 (06) :2445-2448
[8]   5′ flanking variants of resistin are associated with obesity [J].
Engert, JC ;
Vohl, MC ;
Williams, SM ;
Lepage, P ;
Loredo-Osti, JC ;
Faith, J ;
Doré, C ;
Renaud, Y ;
Burtt, NP ;
Villeneuve, A ;
Hirschhorn, JN ;
Altshuler, D ;
Groop, LC ;
Després, JP ;
Gaudet, D ;
Hudson, TJ .
DIABETES, 2002, 51 (05) :1629-1634
[9]   Tumor necrosis factor α is a negative regulator of resistin gene expression and secretion in 3T3-L1 adipocytes [J].
Fasshauer, M ;
Klein, J ;
Neumann, S ;
Eszlinger, M ;
Paschke, R .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 288 (04) :1027-1031
[10]   Isoproterenol inhibits resistin gene expression through a GS-protein-coupled pathway in 3T3-L1 adipocytes [J].
Fasshauer, M ;
Klein, J ;
Neumann, S ;
Eszlinger, M ;
Paschke, R .
FEBS LETTERS, 2001, 500 (1-2) :60-63