Antimicrobial activity of prosthetic heart valve sewing cuffs coated with minocycline and rifampin

被引：10

作者：

Darouiche, RO

Fowler, VG

Adal, K

Kielhofner, M

Mansouri, D

Reller, LB

机构：

[1] Baylor Coll Med, Ctr Prostheses Infect, Houston, TX 77030 USA

[2] St Lukes Episcopal Hosp, Vet Affairs Med Ctr, Houston, TX 77030 USA

[3] Cleveland Clin Fdn, Cleveland, OH 44195 USA

[4] Duke Univ, Med Ctr, Durham, NC 27705 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 02期

关键词：

D O I：

10.1128/AAC.46.2.543-545.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Prosthetic heart valve sewing cuffs coated with minocycline and rifampin exhibited in vitro zones of inhibition against all 52 tested clinical isolates responsible for prosthetic valve endocarditis. An in vitro elution study of these coated sewing cuffs demonstrated residual zones of inhibition against Staphylococcus epidermidis for at least 4 weeks.

引用

收藏

页码：543 / 545

页数：3

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