Impact of mecA gene testing and intervention by infectious disease clinical pharmacists on time to optimal antimicrobial therapy for Staphylococcus aureus bacteremia at a University Hospital

被引:46
作者
Carver, Peggy L. [1 ]
Lin, Shu-Wen [2 ,3 ]
DePestel, Daryl D.
Newton, Duane W. [4 ,5 ,6 ]
机构
[1] Univ Michigan, Coll Pharm, Dept Clin Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan Hlth Syst, Dept Pharm Serv, Ann Arbor, MI USA
[3] Univ Michigan Hlth Syst, Dept Clin Sci, Ann Arbor, MI USA
[4] Univ Michigan Hlth Syst, Clin Microbiol Labs, Ann Arbor, MI USA
[5] Univ Michigan Hlth Syst, Dept Pathol, Ann Arbor, MI USA
[6] Univ Michigan, Sch Med, Ann Arbor, MI 48109 USA
关键词
D O I
10.1128/JCM.00801-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In patients with Staphylococcus aureus bacteremia, intervention by infectious disease clinical pharmacists on the basis of the results of tests for mecA resulted in a 25.4-h reduction in the time to optimal antimicrobial therapy, from 64.7 +/- 36.8 to 39.3 +/- 15.5 h (P = 0.002), which may result in decreased mortality.
引用
收藏
页码:2381 / 2383
页数:3
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