2H-azirine 3-phosphonates:: A new class of chiral iminodienophiles.: Asymmetric synthesis of quaternary piperidine phosphonates

被引：56

作者：

Davis, FA ^{[1
]}

Wu, YZ ^{[1
]}

Yan, HX ^{[1
]}

Prasad, KR ^{[1
]}

McCoull, W ^{[1
]}

机构：

[1] Temple Univ, Dept Chem, Philadelphia, PA 19122 USA

来源：

ORGANIC LETTERS | 2002年 / 4卷 / 04期

关键词：

D O I：

10.1021/ol017289p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Diels-Alder reactions of enantiomerically enriched 2H-azirine 3-phosphonates and dienes stereoselectively furnish optically pure, bicyclic aziridine adducts that on hydrogenation afford the first examples of enantiopure quaternary piperidine phosphonates.

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页码：655 / 658

页数：4

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