Theory of liquid chromatography of mono- and difunctional macromolecules - I. Studies in the critical interaction mode

被引：65

作者：

Gorbunov, A

Trathnigg, B

机构：

[1] Karl Franzens Univ Graz, Inst Chem, A-8010 Graz, Austria

[2] Inst Highly Pure Biopreparat, St Petersburg 197110, Russia

来源：

JOURNAL OF CHROMATOGRAPHY A | 2002年 / 955卷 / 01期

关键词：

critical interaction mode; polymers; polyethylene glcols; retention models;

D O I：

10.1016/S0021-9673(02)00197-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The theory of liquid chromatography of mono- and difunctional polymers based on the model of ideal polymer chain in wide slit-like pores is presented. Analytical equations describing chromatographic behavior of functional macromolecules in both adsorption, exclusion and critical modes are derived and compared with experiments. The focus of this experimental study was on the verification of the theory in chromatography at critical conditions. Chromatographic behavior of low molar mass end-functionalized polyethylene glycols was found to be in a very good qualitative and in a reasonable quantitative agreement with the theory. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：9 / 17

页数：9

共 42 条

[1]

Adrian J, 1999, ANGEW MAKROMOL CHEM, V267, P73

[2] Fractionation of functional polystyrenes, poly(ethylene oxide)s and poly(styrene)-b-poly(ethylene oxide) by liquid chromatography at the exclusion-adsorption transition point [J].