Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas

被引：35

作者：

Salama, Salama A.

Ho, Shu-Leong

Wang, Hui-Qun

Tenhunen, Jukka

Tilgmann, Carola

Al-Hendy, Ayman

机构：

[1] Univ Texas, Med Branch, Dept Obset & Gynecol, Galveston, TX 77555 USA

[2] Univ Hong Kong, Dept Med, Div Neurol, Hong Kong, Hong Kong, Peoples R China

[3] Univ Texas, Med Branch, Sealy Ctr Environm Hlth & Med, Galveston, TX USA

[4] Orion Corp, Orion Pharma, Helsinki, Finland

来源：

FERTILITY AND STERILITY | 2006年 / 86卷 / 01期

关键词：

D O I：

10.1016/j.fertnstert.2005.12.049

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Catechol-O-methyl transferase (COMT) expression is higher in leiomyomas compared with paired normal myometrium. The expression of COMT in leiomyoma cells is hormonally regulated-estrogen downregulates, whereas P and dexamethasone up-regulate, COMT expression.

引用

收藏

页码：259 / 262

页数：4

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