Models of assembly and disassembly of individual microtubules: Stochastic and averaged equations

被引:19
作者
Bolterauer, H
Limbach, HJ
Tuszynski, JA
机构
[1] Univ Giessen, Inst Theoret Phys, D-6300 Giessen, Germany
[2] Univ Alberta, Dept Phys, Edmonton, AB T6G 2J1, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
microtubules; dynamic instability; master equations;
D O I
10.1023/A:1005159215657
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this paper we present solutions of the master equations for the microtubule length and show that the local probability for rescues or catastrophes can lead to bell-shaped length histograms. Conversely, as already known, non-local probabilities for these events result in exponential length histograms. We also derive master equations for a stabilizing cap and obtain a new boundary condition which provides an explanation of the results obtained in dilution and cutting experiments.
引用
收藏
页码:1 / 22
页数:22
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