Correlation of oxidation potential and toxicity in thiobenzamides

被引：14

作者：

Coppola, GM

Anjaria, H

Damon, RE

机构：

[1] Dept. Atherosclerosis Vasc. Biol., Preclinical Research, Sandoz Pharmaceuticals Corporation, East Hanover, NJ 07936

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 02期

关键词：

D O I：

10.1016/0960-894X(95)00571-A

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The oxidation potentials of a series of 4-substituted thiobenzamides (1) were measured by linear sweep voltammetry. When compared with the known toxicological values for these compounds it was found that there is a direct correlation between oxidation potential and toxicity.

引用

页码：139 / 142

页数：4

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