Synthesis of (2R,3S)-(-)-2-phenyl-3-methylaziridine

被引：20

作者：

Galindo, A

Orea, FL

Gnecco, D

Enriquez, RG

Toscano, RA

Reynolds, WF

机构：

[1] UNIV NACL AUTONOMA MEXICO, INST QUIM, MEXICO CITY 04510, DF, MEXICO

[2] UNIV TORONTO, TORONTO, ON M5S 1A1, CANADA

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 17期

关键词：

D O I：

10.1016/S0957-4166(97)00271-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We report the total synthesis of aziridine 3, carried out in a two-step method involving double Walden inversion at the carbon atom bearing the hydroxy group of (1R,2S)-(-)-norephedrine, 1, which was used as starting material. Compound 3 was obtained for the first time as a solid therefore allowing its unambiguous X-ray structure determination. (C) 1997 Elsevier Science Ltd.

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页码：2877 / 2879

页数：3

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