学术探索
学术期刊
新闻热点
数据分析
智能评审

Oncogenic proteins as tumor antigens

被引：113
作者：
Disis, ML
Cheever, MA
机构：
[1] University of Washington, Division of Oncology, Box 36527, Seattle
来源：
CURRENT OPINION IN IMMUNOLOGY | 1996年 / 8卷 / 05期
关键词：
D O I：
10.1016/S0952-7915(96)80079-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Human immune responses to oncogenic proteins have been reported and are continuing to be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or unique cancer-specific oncoproteins has been identified. Immune system based treatments targeting oncogenic proteins have shown therapeutic efficacy in animals models and are currently being translated into human clinical trials.
引用
收藏
页码：637 / 642
页数：6
相关论文
共 42 条
  • [1] Abrams SI, 1996, SEMIN ONCOL, V23, P118
  • [2] PEPTIDE-SPECIFIC ACTIVATION OF CYTOLYTIC CD4(+) T-LYMPHOCYTES AGAINST TUMOR-CELLS BEARING MUTATED EPITOPES OF K-RAS P21
    ABRAMS, SI
    DOBRZANSKI, MJ
    WELLS, DT
    STANZIALE, SE
    ZAREMBA, S
    MASUELLE, L
    KANTOR, JA
    SCHLOM, J
    [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (09) : 2588 - 2597
  • [3] THE EPIDERMAL GROWTH-FACTOR RECEPTOR AS A TARGET FOR THERAPY IN BREAST-CARCINOMA
    BASELGA, J
    MENDELSOHN, J
    [J]. BREAST CANCER RESEARCH AND TREATMENT, 1994, 29 (01) : 127 - 138
  • [4] BERNHARD H, 1995, CANCER RES, V55, P1099
  • [5] SPECIFIC BINDING OF LEUKEMIA ONCOGENE FUSION PROTEIN-PEPTIDES TO HLA CLASS-I MOLECULES
    BOCCHIA, M
    WENTWORTH, PA
    SOUTHWOOD, S
    SIDNEY, J
    MCGRAW, K
    SCHEINBERG, DA
    SETTE, A
    [J]. BLOOD, 1995, 85 (10) : 2680 - 2684
  • [6] BOCCHIA M, 1996, BLOOD, V487, P3587
  • [7] HUMANIZATION OF AN ANTI-P185HER2 ANTIBODY FOR HUMAN CANCER-THERAPY
    CARTER, P
    PRESTA, L
    GORMAN, CM
    RIDGWAY, JBB
    HENNER, D
    WONG, WLT
    ROWLAND, AM
    KOTTS, C
    CARVER, ME
    SHEPARD, HM
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (10) : 4285 - 4289
  • [8] IMMUNITY TO ONCOGENIC PROTEINS
    CHEEVER, MA
    DISIS, ML
    BERNHARD, H
    GRALOW, JR
    HAND, SL
    HUSEBY, ES
    QIN, HL
    TAKAHASHI, M
    CHEN, W
    [J]. IMMUNOLOGICAL REVIEWS, 1995, 145 : 33 - 59
  • [9] T-CELL IMMUNITY TO THE JOINING REGION OF P210BCR-ABL PROTEIN
    CHEN, W
    PEACE, DJ
    ROVIRA, DK
    YOU, SG
    CHEEVER, MA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (04) : 1468 - 1472
  • [10] Disis ML, 1996, J IMMUNOL, V156, P3151
12345