Cytokines for surgeons

被引：84

作者：

Raeburn, CD ^{[1
]}

Sheppard, F ^{[1
]}

Barsness, KA ^{[1
]}

Arya, J ^{[1
]}

Harken, AH ^{[1
]}

机构：

[1] Univ Colorado, Hlth Sci Ctr, Dept Surg, Denver, CO 80262 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2002年 / 183卷 / 03期

关键词：

cytokine; interleukin; surgery; review;

D O I：

10.1016/S0002-9610(02)00781-X

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

All cells maintain continuous communication. Hormones derive constitutively from specialized cells to effect total body homeostasis. Conversely, cytokines are produced sporadically from almost all nucleated cells in response to surgical ischemia/septic challenge. surgical patients are a stew of pulsating cytokines, which serve as the language between all surgically stressed somatic and myeloid cells. Therapeutic manipulation of cytokines has already generated some exhilarating success stories and some crushing disappointments. This introduction to surgically relevant cytokines is presented with the conviction that cytokine-based therapies of surgical patients will (in the future) prove as beneficial to our patients as antibiotics have in the past. (C) 2002 Excerpta Medica, Inc. All rights reserved.

引用

页码：268 / 273

页数：6

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