In vitro activity of PNU-100766 (linezolid), a new oxazolidinone antimicrobial, against Nocardia brasiliensis

被引：30

作者：

Vera-Cabrera, L ^{[1
]}

Gómez-Flores, A ^{[1
]}

Escalante-Fuentes, WG ^{[1
]}

Welsh, O ^{[1
]}

机构：

[1] Univ Hosp, Serv Dermatol, Lab Interdisciplinario Invest Dermatol, Monterrey 64460, NL, Mexico

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 12期

关键词：

D O I：

10.1128/AAC.45.12.3629-3630.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activity of a novel oxazolidinone, linezolid, was studied by comparing the activity of linezolid with those of amikacin, trimethoprim-sulfamethoxazole, and amoxicillin-clavulanic acid against 25 strains of Nocardia brasiliensis isolated from patients with mycetoma. All N. brasiliensis strains tested were sensitive to linezolid (MIC at which 90% of strains are inhibited [MIC90], 2 mug/ml; MIC50, 1 mug/ml). This antimicrobial might constitute a good alternative for treatment of actinomycetoma.

引用

页码：3629 / 3630

页数：2

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