Reduced biocide susceptibility in Candida albicans biofilms

被引：54

作者：

Nett, Jeniel E. ^{[2
]}

Guite, Kristie M. ^{[2
]}

Ringeisen, Alex ^{[3
]}

Holoyda, Kathleen A. ^{[3
]}

Andes, David R. ^{[1
,2
,3
]}

机构：

[1] Univ Wisconsin, Ctr Clin Sci, Dept Cellular & Mol Biol, Madison, WI 53792 USA

[2] Univ Wisconsin, Dept Med, Madison, WI 53792 USA

[3] Univ Wisconsin, Dept Med Microbiol & Immunol, Madison, WI 53792 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 09期

关键词：

D O I：

10.1128/AAC.01656-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Candida biofilm formation is common during infection and environmental growth. We tested the impacts of three biocides (ethanol [EtOH], H2O2, and sodium dodecyl sulfate) on Candida albicans, C. parapsilosis, and C. glabrata biofilms. Higher concentrations of the biocides were required for efficacy against biofilms than for efficacy against planktonic controls. A combination study with two biocides (EtOH and H2O2) and fluconazole demonstrated that the combination had enhanced efficacy.

引用

页码：3411 / 3413

页数：3

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