Phosphine-catalyzed one-pot synthesis of cyclopentenes from electron-deficient allene, malononitrile and aromatic aldehydes

被引：88

作者：

Lu, XY

Lu, Z

Zhang, XM

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

[2] Penn State Univ, Dept Chem, Davey Lab 152, University Pk, PA 16802 USA

来源：

TETRAHEDRON | 2006年 / 62卷 / 2-3期

关键词：

phosphine; cyclopentenes; malononitrile; aromatic aldehydes; electron-deficient allene;

D O I：

10.1016/j.tet.2005.09.100

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A three component reaction of aryl aldehydes and malononitrile with ethyl 2,3-butadienoate catalyzed by triphenylphosphine has been developed. The reaction furnishes highly functionalized cyclopentenes in moderate to good yields in a one-pot process. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：457 / 460

页数：4

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