Immunoglobulin class switch recombination: Will genetics provide new clues to mechanism?

被引:15
作者
Maizels, N
机构
[1] Yale Univ, Sch Med, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Dept Genet, New Haven, CT 06520 USA
关键词
D O I
10.1086/302393
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:1270 / 1275
页数:6
相关论文
共 42 条
[1]   Multiple ATM-dependent pathways: An explanation for pleiotropy [J].
Brown, KD ;
Barlow, C ;
Wynshaw-Boris, A .
AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 64 (01) :46-50
[2]   The role of ATM in DNA damage responses and cancer [J].
Canman, CE ;
Lim, DS .
ONCOGENE, 1998, 17 (25) :3301-3308
[3]   Mismatch repair co-opted by hypermutation [J].
Cascalho, M ;
Wong, J ;
Steinberg, C ;
Wabl, M .
SCIENCE, 1998, 279 (5354) :1207-1210
[4]   Ku80 is required for immunoglobulin isotype switching [J].
Casellas, R ;
Nussenzweig, A ;
Wuerffel, R ;
Pelanda, R ;
Reichlin, A ;
Suh, H ;
Qin, XF ;
Besmer, E ;
Kenter, A ;
Rajewsky, K ;
Nussenzweig, MC .
EMBO JOURNAL, 1998, 17 (08) :2404-2411
[5]   A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: Canonical RNA binding motifs in a sequence-specific duplex DNA binding protein [J].
Dempsey, LA ;
Hanakahi, LA ;
Maizels, N .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (44) :29224-29229
[6]   G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, a role for G-G pairing in immunoglobulin switch recombination [J].
Dempsey, LA ;
Sun, H ;
Hanakahi, LA ;
Maizels, N .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (02) :1066-1071
[7]   DNA-SEQUENCES AT IMMUNOGLOBULIN SWITCH REGION RECOMBINATION SITES [J].
DUNNICK, W ;
HERTZ, GZ ;
SCAPPINO, L ;
GRITZMACHER, C .
NUCLEIC ACIDS RESEARCH, 1993, 21 (03) :365-372
[8]   Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV [J].
Frank, KM ;
Sekiguchi, JM ;
Seidl, KJ ;
Swat, W ;
Rathbun, GA ;
Cheng, HL ;
Davidson, L ;
Kangaloo, L ;
Alt, FW .
NATURE, 1998, 396 (6707) :173-177
[9]   Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process [J].
Frey, S ;
Bertocci, B ;
Delbos, F ;
Quint, L ;
Weill, JC ;
Reynaud, CA .
IMMUNITY, 1998, 9 (01) :127-134
[10]   Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85α [J].
Fruman, DA ;
Snapper, SB ;
Yballe, CM ;
Davidson, L ;
Yu, JY ;
Alt, FW ;
Cantley, LC .
SCIENCE, 1999, 283 (5400) :393-397