Cul-catalyzed tandem intramolecular amidation using gem-dibromovinyl systems

被引：104

作者：

Yuen, J ^{[1
]}

Fang, YQ ^{[1
]}

Lautens, M ^{[1
]}

机构：

[1] Univ Toronto, Dept Chem, Davenport Chem Labs, Toronto, ON M5S 3H6, Canada

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 04期

关键词：

D O I：

10.1021/ol052840u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Imidazoindolones are present as the key structural motif in the family of antifungals, fumiquinazolines, and the antagonist asperlicin. The first example of a Cul-catalyzed tandem intramolecular amidation forming substituted imidazoindolones from readily accessible ortho gem-dibromovinylanilines is described.

引用

页码：653 / 656

页数：4

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