Etiology of fibromyalgia: The possible role of infection and vaccination

被引:108
作者
Buskila, Dan [1 ]
Atzeni, Fabiola [2 ]
Sarzi-Puttini, Piercarlo [2 ]
机构
[1] Ben Gurion Univ Negev, Dept Internal Med H, Soroka Med Ctr, IL-84101 Beer Sheva, Israel
[2] L Sacco Univ Hosp, Dept Rheumatol, Milan, Italy
关键词
Fibromyalgia; Infection; Vaccination; Chronic fatigue syndrome;
D O I
10.1016/j.autrev.2008.07.023
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Fibromyalgia syndrome (FMS), a condition characterized by widespread pain and diffuse tenderness, is considered a multifactorial disorder. FMS is now recognized as one of the central" pain syndromes. Environmental and genetic factors play a role in the pathogenesis of FMS. Various triggers including trauma and stress as well as infections, may precipitate the development of FMS. Certain infections including hepatitis C virus, HIV and Lyme disease have been temporally associated with the development of FMS. There is some evidence for the possible role of vaccinations in triggering the development of FMS and related syndromes, however this association remains to be established. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:41 / 43
页数:3
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