Multiple generators in the auditory automatic discrimination process in humans

被引：56

作者：

Kasai, K

Nakagome, K

Itoh, K

Koshida, I

Hata, A

Iwanami, A

Fukuda, M

Hiramatsu, KI

Kato, N

机构：

[1] Univ Tokyo, Fac Med, Dept Neuropsychiat, Bunkyo Ku, Tokyo 1138655, Japan

[2] Univ Tokyo, Grad Sch Med, Dept Cognit & Speech Sci, Bunkyo Ku, Tokyo 1138655, Japan

[3] Teikyo Univ, Sch Med, Mizonokuchi Hosp, Dept Psychiat, Kanagawa, Japan

[4] Tokyo Engn Univ, Dept Informat Technol, Tokyo, Japan

[5] Gunma Univ, Sch Med, Dept Neuropsychiat, Gunma, Japan

[6] Univ Ryukyus, Fac Med, Dept Neuropsychiat, Okinawa, Japan

来源：

NEUROREPORT | 1999年 / 10卷 / 11期

关键词：

event-related potentials; high resolution; EEG; mismatch negativity; scalp current density; topography;

D O I：

10.1097/00001756-199908020-00008

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

To reveal the spatiotemporal characteristics of the auditory automatic discrimination process, mismatch negativity (MMN) generators were assessed with a high-resolution EEG system (128ch) and scalp current density (SCD) analysis. Ten normal volunteers participated in the study. Event-related potentials were recorded during a selective attention task. Sequential SCD mappings revealed that a current sink/source combination in the left temporal regions and a current sink in the right frontotemporal regions appeared around 200 msec irrespective of the ear of stimulation. Moreover, a parietal sink/source combination was demonstrated on the right hemisphere around 240 ms irrespective of the ear of stimulation. These findings demonstrate that the auditory automatic change detection process is, both spatially and temporally, a multiple-generated system. NeuroReport 10:2267-2271 (C) 1999 Lippincott Williams & Wilkins.

引用

页码：2267 / 2271

页数：5

共 20 条

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