Cytosines do it, thymines do it, even pseudouridines do it - Base flipping by an enzyme that acts on RNA

被引:14
作者
Cheng, XD [1 ]
Blumenthal, RM
机构
[1] Emory Univ, Sch Med, Dept Biochem, Atlanta, GA 30322 USA
[2] Med Coll Ohio, Dept Microbiol & Immunol, Toledo, OH 43614 USA
[3] Med Coll Ohio, Program Bioinformat & Proteom Genom, Toledo, OH 43614 USA
关键词
D O I
10.1016/S0969-2126(02)00710-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In the December 28, 2001 issue of Cell, Hoang and Ferré-D'Amaré report the structure of a tRNA pseudouridine synthase, showing the target uridine flipped out from the tRNA and confirming that base flipping is not limited to enzymes that act on DNA.
引用
收藏
页码:127 / 129
页数:3
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