Sonochemical Coatings of ZnO and CuO Nanoparticles Inhibit Streptococcus mutans Biofilm Formation on Teeth Model

被引:115
作者
Eshed, Michal [1 ]
Lellouche, Jonathan [1 ,2 ]
Matalon, Shlomo [3 ]
Gedanken, Almon [1 ]
Banin, Ehud [2 ]
机构
[1] Bar Ilan Univ, Dept Chem, Kanbar Lab Nanomat, Bar Ilan Inst Nanotechnol & Adv Mat, IL-52900 Ramat Gan, Israel
[2] Bar Ilan Univ, Biofilm Res Lab, Bar Ilan Inst Nanotechnol & Adv Mat, Mina & Everard Goodman Fac Life Sci, IL-52900 Ramat Gan, Israel
[3] Tel Aviv Univ, Dept Oral Rehabil, Sch Dent Med, IL-69978 Tel Aviv, Israel
关键词
ORAL STREPTOCOCCI; SILVER;
D O I
10.1021/la301432a
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Antibiotic resistance has prompted the search for new agents that can inhibit bacterial growth. We recently reported on the antibiofilm activities of nanosized ZnO and CuO nanoparticles (NPs) synthesized by using sonochemical irradiation. In this study, we examined the antibacterial activity of ZnO and CuO NPs in a powder form and also examined the antibiofilm behavior of teeth surfaces that were coated with ZnO and CuO NPs using sonochemistry. Free ZnO and CuO NPs inhibited biofilm formation of Streptococcus mutans. Furthermore, by using the sonochemical procedure, we were able to coat teeth surfaces that inhibited bacterial colonization.
引用
收藏
页码:12288 / 12295
页数:8
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